Figure 4.

Anti-EFG1 2′OMe Effect on Simulated Human Body Fluids (AS, AU, and Horse Blood)

(A) Percent inhibition (%) of filamentous forms at different time points (6, 8, 10, and 24 h for AS and AU; 48 h for horse blood). (B) Levels of EFG1 gene expression for C. albicans SC5314 obtained by the Pfaffl method, after treatment with 40 nM ASO in the presence of different simulated human body fluids (AS and AU at 24 h and horse blood at 48 h). Error bars represent SD. *Significant difference between 6 h and the other times tested (p < 0.05); ⁺Significant difference between untreated and treated cells (p < 0.05).