Table 3.
Brain Region |
t | PFWE | Cluster Size (k) | MNI Coordinates |
||||
---|---|---|---|---|---|---|---|---|
Lobe | Area | Side | x | y | z | |||
Small-Volume Correction | ||||||||
TD: Activation by ER (Decrease Neg > Look Neg) | ||||||||
Parietal | Angular gyrus, superior/inferior parietal lobe | L | 5.57 | .006 | 327 | −46 | −56 | 40 |
Frontal | Superior/middle frontal gyrus (dlPFC) | L | 4.71 | .038 | 231 | −30 | 18 | 42 |
TD: Modulation by ER (Look Neg > Decrease Neg) | NS | |||||||
CD: Activation by ER (Decrease Neg > Look Neg) | NS | |||||||
CD: Modulation by ER (Look Neg > Decrease Neg) | NS | |||||||
TD > CD: Activation by ER (Decrease Neg > Look Neg) | ||||||||
Parietal | Angular gyrus, mid occipital/inferior parietal lobe | L | 4.85 | .009 | 129 | −30 | 18 | 40 |
Frontal | Inferior/middle frontal gyrus (dlPFC) | L | 4.55 | .023 | 118 | −40 | −58 | 36 |
TD > CD: Modulation by ER (Look Neg > Decrease Neg) | NS | |||||||
Whole-Brain Correction | ||||||||
TD: Activation by ER (Decrease Neg > Look Neg) | ||||||||
Parietal | Angular gyrus, superior/inferior parietal, middle occipital lobe | L | 5.57 | <.001 | 972 | −46 | −56 | 40 |
Frontal | Middle/superior frontal lobe | L | 4.71 | .028 | 385 | −30 | 18 | 42 |
TD: Modulation by ER (Look Neg > Decrease Neg) | NS | |||||||
CD: Activation by ER (Decrease Neg > Look Neg) | NS | |||||||
CD: Modulation by ER (Look Neg > Decrease Neg) | ||||||||
Frontal | Olfactory, anterior cingulate, caudate, putamen, OFC | L/R | 6.57 | .012 | 180 | −18 | 30 | −6 |
Temporal | Thalamus, hippocampus, lingual, precuneus, parahippocampus | L/R | 6.56 | <.001 | 412 | −6 | −24 | 6 |
Occipital | Fusiform gyrus, inferior/middle occipital gyrus, lingual, calcarine | R | 4.96 | .003 | 238 | 30 | −84 | −10 |
Occipital | Middle, inferior, superior occipital lobe | L | 4.57 | .008 | 195 | −22 | −98 | 8 |
TD > CD: Activation by ER (Decrease Neg > Look Neg) | ||||||||
Parietal | Angular, inferior parietal, mid occipital lobe | L | 4.64 | .046 | 231 | −38 | −58 | 34 |
TD > CD: Modulation by ER (Look Neg > Decrease Neg) | NS |
CD, conduct disorder; dlPFC, dorsolateral prefrontal cortex; ER, emotion regulation; FWE, familywise error; L, left; MNI, Montreal Neurological Institute; Neg, negative; NS, not significant; OFC, orbitofrontal cortex; R, right; TD, typically developing.