Figure 2.

The Computational Model Design

(A) Schematic describing the finite elements.

(B) Schematic of growth methodology in the model, red wire plot, the reference shape of the element; blue wire plot, the preferred shape of the element.

(C) Elastic forces generated by elements upon deformation.

(D) Simulation of clone (dark blue) growth surrounded by non-growing tissue (i) the oriented growth input (ii) Initial state of a tissue fragment, (iii) after application of growth in (i). (iv) Tissue in (ii) after growing with the same rates at an orientation angle of zero degrees.

(E) Initial mesh of the simulations, at 48 h AEL. See also Figure S1.