REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
H3K27ac antibody	Abcam	Cat#Ab4729; RRID: AB_2118291
IgG antibody	Millipore	Cat#12-370; RRID: AB_145841
Brd4 antibody	Bethyl Laboratories	Cat#A301-985A; RRID: AB_1576498
GFP antibody (rabbit)	Torrey Pines Biolabs	Cat#TP401; RRID: AB_10013661
Donkey anti-rabbit IgG (AlexaFluor-488-conjugated)	ThermoFisher Scientific	Cat#A21206; RRID: AB_141708
Critical Commercial Assays
RNAqueous Micro Total RNA isolation kit	Ambion	Cat#AM1931
SmartSeq2 V4 kit	Takara Clontech	Cat#634889
Nextera XT DNA library preparation kit	Illumina	Cat#FC-131-1024
Chromium Single Cell 3’ Library and Gel Bead Kit v2	10X Genomics	Cat#120267
Chromium Chip E single cell ATAC kit	10X Genomics	Cat#1000086
Chromium Single Cell ATAC Library and Gel Bead Kit	10X Genomics	Cat#PN-1000111
Qubit High sensitivity DNA kit	ThermoFisher Scientific	Cat#Q32854
Tapestation High sensitivity D1000	Agilent	Cat#5067-5584
KAPA Library Quantification Kit	Kapa Biosystems	Cat#KK4835
Nextera DNA kit	Illumina	Cat#FC-121-1030
NEB Next High-Fidelity 2X PCR Master Mix	New England Biolabs	Cat#M0543S
NextSeq 500/550 High Output Kit v2 (75 cycles)	Illumina	Cat#FC-404-2005
NextSeq 500/550 High Output Kit v2.5 (150 cycles)	Illumina	Cat#20024907
Dynabeads Protein A	Life Technologies	Cat#10006D
NEBNext Ultra DNA Library Prep kit	New England Biolabs	Cat#E7370S
Agencourt AMPure XP beads	Beckman Coulter	Cat#A63880
Hybloc Competitor DNA, a Cot-1 DNA equivalent	Applied Genetics Laboratories	Cat#CHB
Nimblegen SeqCap EZ hybridization and wash kit	Roche	Cat#05634261001
V2 Nimblegen SeqCap EZ accessory kit	Roche	Cat#07145594001
Dynabeads Streptavidin M270	Life Technologies	Cat#65305
300-cycle MiSeq Reagent Kit v2	Illumina	Cat#MS-102-2002
Long Range HotStart PCR kit	KAPA Biosystems	Cat#KK3501
E.Z.N.A. Endo Free Plasmid Mini Kit II	Omega BioTek	Cat#D6950-02
Endofree maxi prep kit	Qiagen	Cat#12362
Vectashield with DAPI	Vector Laboratories	Cat#H-1200
Deposited Data
RNA-seq data (bulk)	This paper	ShinyApp GEO: GSE121526
ChIP-seq data	This paper	GEO: GSE121329
Capture-C data	This paper	GEO: GSE121324
ATAC-seq data (bulk)	This paper	ShinyApp; GEO: GSE121318
sc-RNA (SmartSeq2)	This paper	GEO: GSE130500
sc-RNA and sc-ATAC (10X Chromium)	This paper	GEO: GSE131688
RNA-seq following TF knockouts	This paper	GEO: GSE121331