Figure 6.

Disease Associations for Novel Peptide-Receptor Pairs

Diseases associated with paired receptors and peptide precursors from https://www.opentargets.org. Open Targets presents associations with therapeutic areas by agglomerating data; e.g., genome-wide associations, genetic variants, expression and animal models. Disease association scores between 0 and 1 (color intensity) summarize the strength of evidence. For precursors with disease correlation similar to the associated receptor target, the Pearson correlation value is indicated. UniProt names for precursors are shown, with peptide library designation in parentheses (Table S4).