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. 2019 Oct 31;179(4):895–908.e21. doi: 10.1016/j.cell.2019.10.010

Figure 7.

Figure 7

Expansion of the Human Peptidergic Receptor Signaling System

The new pairings (colored lines) increase the number of known ligand-receptor connections (edges) from 348 to 407 (putative peptide ligands from 185 to 214 and putative peptide receptors from 120 to 130). Ligand-receptor systems are shown with increasing ligand-to-receptor ratios (top to bottom). There are more ligands per receptor in both the established and novel peptidergic receptor systems.