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. 2019 Sep 7;117(9):1599–1614. doi: 10.1016/j.bpj.2019.08.039

Table 2.

Parameters Used to Describe the Unfolding and Refolding of the Talin Rod Domains R1–R12

Talin domain 1 2 3 4 5 6 7–8 9 10 11 12
Folded size (nm) 5 5 5 5 5 5 5 5 5 5 5
Unfolded size (nm) 69.2 52.4 49.6 52.4 64 60.4 118.4 66.8 63.2 66.4 62.8
kfu(s−1) 4.2 × 10−6 1.7 × 10−8 0.018 4.2 × 10−6 2.5 × 10−5 2.5 × 10−5 4.2 × 10−6 4.2 × 10−6 2.5 × 10−5 2.5 × 10−5 1.7 × 10−8
Δxfu (nm) 3.1 3.4 5.7 3.1 4.1 4.1 3.1 3.1 4.1 4.1 3.4
kuf(s−1) 1.606 0.1318 1 × 106 22.387 2.57 2.57 22.387 123 123 123 123
Δxuf (nm) 4.28 4.14 9.86 4.04 11.5 11.5 13.6 10.35 10.35 10.35 10.35

Parameter fits were based on the data of Yao et al. (69,70).