Table 1.
Baseline demographic characteristics of age, BMI and nuclear anomalies in buccal cells.
| Parameter | All | Young (20–59.9 years) | Old (60 + years) | P |
|---|---|---|---|---|
| Subjects [number] | 163 | 74 | 89 | 0.000 |
| Age [years] | 61.7 (±26.7) | 31.2 (±10.1) | 82.8 (±6.5) | 0.000 |
| BMI [kg/m2] | 26.84 (±5.14) | 23.6 (±3,2) | 29.2 (±5.0) | 0.000 |
| Buccal Micronucleus Cytome Assay | ||||
| MN cells [per 1000 diff. cells] | 0.76 (±0.61) | 0.27 (±0.36) | 1.17 (±0.46) | 0.000 |
| MN total [per 1000 diff. cells] | 0.85 (±0.66) | 0.34 (±0.44) | 1.28 (±0.49) | 0.000 |
| Nuclear buds [per 1000 diff. cells] | 0.88 (±0.78) | 0.58 (±0.56) | 1.13 (±0.84) | 0.000 |
| Binucleated cells [per 1000 diff. cells] | 18.7 (±9.3) | 12.0 (±4.8) | 24.2 (±8.6) | 0.000 |
| Karyorrhectic cells [per 1000 cells] | 16.9 (±10.5) | 9.6 (±5.6) | 22.9 (±9.9) | 0.000 |
| Karyolytic cells [per 1000 cells] | 46.5 (±29.0) | 29.7 (±23.8) | 59.9 (±25.8) | 0.000 |
| Pyknotic cells [per 1000 cells] | 1.24 (±0.96) | 1.23 (±0.92) | 1.25 (±1.00) | 0.195 |
Data are means ± SD; p-values for differences between “Young” and “Old” subjects were calculated using Mann-Whitney-U-Test; significant differences are highlighted using bold formatting. For this table data from the Vienna Active Ageing Study and Wallner et al. (14) were combined.