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. 2019 Nov 1;5(10):e02565. doi: 10.1016/j.heliyon.2019.e02565

Table 1.

Selected phytochemicals with antiviral activities present COA®-FS herbal medicineand its component plants.

Compounds Name Plant name Extracts Plant parts Literature Reference COA-FS herbal medicine
GC-MS Extracts Reference
EGA Spondias mombin, Carica papaya Hydroethanolic, Leaf (Shin et al., 2005) Nwabuife, 2019 + Ethanolic, Hexane, Boadu, 2019; Nwabuife, 2019
CHD Azadirachta indica, Vernonia amygdalina, Carica papaya Methanolic, hexane, ethanol, ethylacetate, Dichloromethane Leaf (Dineshkumar and Rajakumar, 2017) Boadu, 2019; Nwabuife, 2019 + Ethanol, hexane Boadu, 2019; Nwabuife, 2019
LNT Azadirachta indica, Vernonia amygdalina Chloroform, Dichloromethane Leaf (Siddiqui et al., 2006) Boadu, 2019 + Dichloromethane Boadu, 2019
BIT Carica papaya Hydrothanolic Seed, leaf (Kermanshai et al., 2001) + Ethanolic Boadu, 2019
GA (methyl salicylate) Persea Americana Methanolic Pulp, Leaf (Hurtado-Fernández et al., 2014) + Standard Boadu, 2019
IST Vernonia amygdalina Chloroform, Dichloromethane, ethanol, Leaf (Adewole et al., 2018) Boadu, 2019 + Dichloromethane Boadu, 2019
STG Carica papaya, Persea Americana, Vernonia amygdalina, Azadirachta indica Petroleum ether, Hydroethanolic, hexane, Dichloromethane, ethylacetate, ethanol Leaf (Rashed et al., 2013; Monika and Geetha, 2015; Boadu, 2019; Nwabuife, 2019) + Hexane, Dichloromethane, ethylacetate Boadu, 2019; Nwabuife, 2019
PTA Carica papaya, Azadirachta indica Methanolic, Crude oil, hexane, Dichloromethane, ethylacetate, ethanol Leaf (Sajin et al., 2015; Boadu, 2019; Babatunde et al., 2019) + Hexane, ethylacetate Boadu, 2019; Nwabuife, 2019
NGN Persea Americana, Carica papaya Methanolic, Ethylacetate Leaf (Hurtado-Fernández et al., 2014; Nwabuife, 2019 - Methanolic, Ethylacetate
K7G Carica papaya Ethanolic, aqueous Fruit/pulp, dry leaf (Kongkachuichai and Charoensiri, 2010; Lako, 2007) - ND
EGCG Persea Americana HydroMethanolic seed (Calderón-Oliver et al., 2015) - ND
LUT Vernonia amygdalina, Carica papaya Ethanolic, methanolic Leaf, Fruit/pulp (Igile et al., 1995) - ND
GER Spondiasmombin Hydroalcoholic Leaf (Mukhtar et al., 2008) - ND
APG Carica papaya Ethanolic, aqueous Fruit/pulp Franke et al., 2004 - ND
FST Carica papaya Ethanolic, aqueous Fruit/pulp Lako, 2007 - ND

Key: + means present, - means not present, ND means not detected.