Figure 6.
Ad5-PC-Cured Mice Exhibit a Tumor-Specific and Long-Term Immune Memory
(A) Mice that had been cured were re-challenged with 5 × 106 H22 cells on days 90 and 150 post-inoculation. Naive mice were used as a control. The day that mice received the re-challenge was regarded as day 0 in the survival curves. (B) Cured mice from H22 ascetic tumor or hepa1-6 solid HCC were subcutaneously injected with 5 × 106 H22 cells. Mice were sacrificed for tumor measure 16 days after re-challenge with H22 cells. i.p., injected peritoneally; s.c., injected subcutaneously. ***p < 0.001.