Figure 7.

Oncolytic Efficacy of Ld0-GFP in the Subcutaneous Xenograft Model Bearing Human HCC

(A) Treatment scheme. s.c., subcutaneous. (B) Growth of vehicle-, d0-GFP- or Ld0-GFP-treated Huh7 xenografts in nude mice (n = 8). (C) Body weight of the treated nude mice was monitored in the subcutaneous Huh7 xenograft model. (D) Growth of vehicle-, d0-GFP- or Ld0-GFP-treated Hep3B xenografts in nude mice (n = 8). (E) Body weight of the treated nude mice was monitored in the subcutaneous Hep3B xenograft model. The statistical significance of the intergroup comparisons of tumor volumes or body weight was analyzed using a repeated-measure ANOVA. All values are presented as the mean ± SEM. *p < 0.05, **p < 0.01, ns, not significant.