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. 2019 Sep 10;27(11):1930–1938. doi: 10.1016/j.ymthe.2019.08.020

Table 4.

Disease Response and PET SUV Changes after a Single Dose of Intravenous Seprehvir

Patient No. Day 14 CT/MRI Day 14 PET Day 28 CT/MRI Day 28 PET Time from Tx to Death (months)
HSV01 stable disease SUV stable NA NA 0.5
HSV02 PD SUV ↑ PD SUV ↑ 11.5
HSV03 stable disease ND PD ND 1
HSV04 stable disease SUV stable stable disease SUV stable 26a
HSV05 PD ND ND ND 3.5
HSV06 PD SUV ↑ NA NA 2
HSV07 NEb NEb PD PD 7
HSV08 PD SUV ↑↑ PD SUV ↑ 11
HSV09-I stable disease SUV stable stable disease SUV ↓
HSV09-II NA NA PD SUV ↑ 6a

NA, not applicable; ND, not done; NE, not evaluable; PD, progressive disease; SUV, standardized uptake valuemax; Tx, treatment.

a

Patient is still alive so time from treatment to follow-up.

b

Tumor resected on day 7 for biopsy specimen and was the only site of active disease at the time.