Table 3.
Association between allergy-related factors at 12 and 32 weeks of gestation and CB CCL17 and CP-DEI.a
| Allergy-related factors | OR (95% CI) | P-value |
|---|---|---|
| Maternal environment (12 weeks of gestation) | ||
| family size (number)b | 0.65 (0.48–0.89) | 0.01 |
| dog ownershipc (yes) | 2.28 (0.68–7.67) | 0.18 |
| cat ownershipc (yes) | 0.42 (0.18–1.00) | 0.05 |
| total fiber intake/total fat intake | 6.28 (0.13–309.30) | 0.36 |
| fermented foodd intake/total energy intake (g/kcal) | 3.30 (0.01–1143.04) | 0.69 |
| CB CCL17 level (100 pg/mL) | 1.00 (1.00–1.00) | 0.02 |
| Maternal environment (32 weeks of gestation) | ||
| family size (number)b | 0.69 (0.52–0.92) | 0.01 |
| dog ownershipc (yes) | 2.33 (0.70–7.78) | 0.17 |
| cat ownershipc (yes) | 0.44 (0.19–1.00) | 0.05 |
| total fiber intake/total fat intake | 1.06 (0.03–41.16) | 0.97 |
| fermented foodd intake/total energy intake (g/kcal) | 3.50 (0.01–1286.43) | 0.68 |
| CB CCL17 level (100 pg/mL) | 1.00 (1.00–1.00) | 0.01 |
a
All parameters were calculated using logistic regression analysis adjusted by maternal allergy; statistically significant (P ≤ 0.05) values are in bold. Sample sizes were as follows: 214 (DEI-positive) and 70 (DEI-negative) at 12 weeks of gestation, and 217 (DEI-positive) and 73 (DEI-negative) at 32 weeks of gestation. Abbreviations: CP-DEI, cumulative prevalence of dermatitis in early infancy.
b
Family size was considered to be the same at 12 and 32 weeks of gestation.
c
Blanks correspond to no pets.
d
Fermented foods were summed as the intake of pickles, natto, soy-sauce, and miso-paste