Table 4-1.

SDIs of 4 phyla and a significant genus in the maternal fecal microbiota at 12 weeks of gestation.^a

12 weeks of gestation	Positive			Negative			P valueb
	median	IQR	n	median	IQR	n
Maternal allergy
Total	3.73	3.44–3.90	n = 35	3.79	3.64–4.03	n = 21	0.25
Firmicutes	3.50	3.25–3.74		3.53	3.23–3.91		0.59
Proteobacteria	1.32	1.01–1.54		1.08	0.94–1.36		0.13
Actinobacteria	1.57	1.10–1.73		1.58	1.30–1.77		0.85
Bacteroidetes	1.90	1.68–2.25		2.03	1.81–2.27		0.71
Bacteroides sp.	1.53	1.23–1.68		1.46	1.26–1.69		0.81
CP-DEI
Total	3.78	3.63–3.97	n = 32	3.58	3.30–3.78	n = 10	0.05
Firmicutes	3.59	3.28–3.84		3.41	3.22–3.64		0.14
Proteobacteria	1.14	0.94–1.42		1.50	1.21–1.60		0.07
Actinobacteria	1.59	1.29–1.73		1.65	0.97–1.75		0.94
Bacteroidetes	1.99	1.74–2.33		2.00	1.69–2.25		0.92
Bacteroides sp.	1.51	1.23–1.69		1.60	1.40–1.80		0.37
AD and/or FA at 10 months
Total	3.65	3.40–3.86	n = 9	3.80	3.63–3.99	n = 24	0.56
Firmicutes	3.68	3.37–3.91		3.56	3.31–3.79		0.56
Proteobacteria	1.22	1.14–1.41		1.25	1.03–1.56		0.80
Actinobacteria	1.70	1.47–1.77		1.61	1.26–1.79		0.65
Bacteroidetes	1.74	1.52–2.49		2.04	1.80–2.33		0.54
Bacteroides sp.	1.41	1.09–1.65		1.56	1.40–1.70		0.25

^aData represent the maternal and offspring's atopic manifestations, separately. Abbreviations: SDI, Shannon diversity index; CP-DEI, cumulative prevalence of dermatitis in early infancy.

^bCalculated using Wilcoxon rank sum test