Table 1.
Baseline characteristics of patients with metastatic gastric cancer.
| Characteristic, n (%) | Total (n = 267) | Multimodality treatment (n = 114) | Chemotherapy only (n = 153) | P-value |
|---|---|---|---|---|
| Age (years), mean ± SD | 56.4 ± 12.5 | 55.3 ± 11.9 | 57.1 ± 12.8 | 0.242 |
| Sex | 0.257 | |||
| Male | 181 (67.8) | 73 (64.0) | 108 (70.6) | |
| Female | 86 (32.2) | 41 (36.0) | 45 (29.4) | |
| Differentiation | 0.565 | |||
| Well/median | 61 (22.8) | 28 (24.6) | 33 (21.6) | |
| Poor | 206 (77.2) | 86 (75.4) | 120 (78.4) | |
| HER2 status | 0.520 | |||
| Positive | 54 (20.2) | 26 (22.8) | 28 (18.3) | |
| Negative | 98 (36.7) | 43 (37.7) | 55 (35.9) | |
| Unknown | 115 (43.1) | 45 (39.5) | 70 (45.8) | |
| Tumor location | 0.496 | |||
| Upper | 79 (29.6) | 29 (25.4) | 50 (32.7) | |
| Middle | 86 (32.2) | 36 (31.6) | 50 (32.7) | |
| Lower | 94 (35.2) | 45 (39.5) | 49 (32.0) | |
| Diffuse | 8 (3.0) | 4 (3.5) | 4 (2.6) | |
| CA19–9 level | 0.184 | |||
| Normal | 161 (60.3) | 74 (64.9) | 87 (56.9) | |
| Elevated | 106 (39.7) | 40 (35.1) | 66 (43.1) | |
| CEA level | 0.062 | |||
| Normal | 144 (53.9) | 69 (60.5) | 75 (49.0) | |
| Elevated | 123 (46.1) | 45 (39.5) | 78 (51.0) | |
| Metastatic site | ||||
| Peritoneum | 85 (31.8) | 43 (37.7) | 42 (27.5) | 0.075 |
| Liver | 75 (28.1) | 27 (23.7) | 48 (31.4) | 0.167 |
| Krukenberg | 38 (14.2) | 22 (19.3) | 16 (10.5) | 0.041 |
| Lung | 16 (6.0) | 7 (6.1) | 9 (5.9) | 0.930 |
| Bone | 25 (9.4) | 7 (6.1) | 18 (11.8) | 0.119 |
| Non-regional lymph nodes | 117 (43.8) | 45 (39.5) | 72 (47.1) | 0.217 |
| Other | 61 (22.8) | 25 (21.9) | 36 (23.5) | 0.925 |
| Number of metastatic sites | 0.529 | |||
| 1 | 138 (51.7) | 63 (55.3) | 75 (49.0) | |
| 2 | 80 (30.0) | 33 (28.9) | 47 (30.7) | |
| ≥3 | 49 (18.3) | 18 (15.8) | 31 (20.3) | |
| Curative surgery | 99 (37.1) | 46 (40.4) | 53 (34.6) | 0.339 |
| Neoadjuvant treatment | 23 (23.2) | 10 (21.7) | 13 (24.5) | 0.257 |
| Adjuvant treatment | 85 (85.9) | 39 (84.8) | 46 (86.8) | 0.225 |
| Follow-up period (months), median (95%CI) | 63.5 (50.4–76.5) | 60.4 (48.3–72.5) | 63.5 (44.7–82.3) | 0.492 |