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. 2019 Nov 8;19:283. doi: 10.1186/s12935-019-0998-4

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Knockdown of TRIM27 inhibited the growth of ESCC cells. a, b The cell proliferation rate detected at 12 h, 24 h and 48 h after transfection with siNC, siTRIM27-1 and siTRIM27-2 in KYSE150 and TE-11 cells respectively, *p < 0.05 vs siNC, ***p < 0.001 vs siNC. c Cell apoptosis profile was upregulated in siTRIM27 transfected cells as indicated, ***p < 0.001 vs siNC. d The level of 2-NBDG was suppressed in siTRIM27 transfected cells, ***p < 0.001 vs siNC. e, f The protein level of GLUT1, HKII, cleaved caspase-3, AKT and p-AKT examined in different cells as indicated, ***p < 0.001 vs siNC