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. 2019 Nov 8;18:356. doi: 10.1186/s12936-019-2989-2

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 8 — Pfs230D1+ protein induced functional antibodies in mice. a Antibody level in each serum was determined against corresponding immunogen by ELISA. Individual (dots) and geometric mean (bars) ELISA units are shown. In each immunogen groups, there was a significant difference among the 3-dose groups (p = 0.001 for Pfs230-C1, and p = 0.015 for Pfs230-D1+ groups by Kruskal–Wallis tests), and significant difference between two groups are shown with asterisks (Dunn’s multiple comparisons test): *p < 0.05; **p < 0.01. b Total IgG from each group was tested at 750 µg/mL with complement in SMFA. Oocyst count in individual mosquito (dots) and the arithmetic mean (bars) are shown with % transmission-reducing activity (%TRA) calculated against control group. All inhibitions were significant (p < 0.001 for all by the ZINB model)