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. 2019 Nov 8;19:284. doi: 10.1186/s12935-019-1007-7

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Knockdown of TRIM11 inhibited the growth of chordoma cells. a, b The cell proliferation rate was reduced in MUG-Chor1 or U-CH1 cells that transfected with siTRIM11-1 and siTRIM11-2, respectively; *p < 0.05 vs siNC, ***p < 0.001 vs siNC. c Knockdown of TRIM11 promoted the apoptosis of MUG-Chor1 or U-CH1 cells that transfected with siTRIM11-1 and siTRIM11-2, respectively; ***p < 0.001 vs siNC. d, e Western bolt was used to examine the protein content of TRIM11, XIAP, cleaved caspase-3 in MUG-Chor1 or U-CH1 cells that transfected with siTRIM11-1 and siTRIM11-2, respectively; ***p < 0.001 vs siNC