Figure 7.

Z-scores of metabolic and spatial variables in control and treated xenografts and organoids. Heatmap of Z-scores across treatment groups and model systems (organoid and xenograft). Each Z-score is calculated for each sample of a given treatment group (i_Rx) and variable (j) as the difference between the mean variable per sample and the mean variable across all organoids of the corresponding treatment group (organoid_Rx) divided by the standard deviation of the organoid treatment group. Z-score differences within a single treatment group represent variability across samples. Gray boxes indicate samples without a value for a given variable, specific to xenograft and organoid treatment groups with a single population.