Fig.6.

Effects of TEMT administration on CSF levels of soluble Aβ_1-40 (A), soluble Aβ_1-42 (B), and oligomeric Aβ (C) following 2 months of TEMT (Day60) compared to levels at Baseline for all individual subjects. D) For subjects that showed a decrease in CSF Aβ oligomers following 2 months of TEMT (n = 3), combined performance on the ADAS-cog was stable on Day60 compared to Baseline. For subjects that showed an increase in CSF Aβ oligomer levels after 2 months of TEMT (n = 5), a sizable 5+ point improvement in their combined ADAS-cog score was present on Day60 versus Baseline.