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. Author manuscript; available in PMC: 2019 Nov 8.
Published in final edited form as: J Invest Dermatol. 2019 Jun 15;139(11):2263–2271.e5. doi: 10.1016/j.jid.2019.03.1163

Figure 5. Evolutionary trajectories of select BSC samples.

Figure 5.

Analysis of the evolutionary trajectories for BSC samples demonstrated mutations in PTCH1 before mutations in ARID1A, and then followed by TP53 and SCC driver genes in several BSC samples including the two displayed. Shaded regions represent clones and subclones. BSC, basosquamous carcinoma; GL, germline; SCC, squamous cell carcinoma.