Figure 6.

PA imaging (A) and intensity (B) in the tumor region after intravenously injected MPDA-PEG-PTX nanoparticles are recorded at different time points after intravenous administration. Local temperature (C) and thermal images (D) of four groups A549 tumor-bearing mice treated with PBS and MPDA-PEG-PTX (100 μL, 4 mg mL⁻¹) under NIR laser irradiation (808 nm, 2 W cm⁻²) for 5 mins at 2-hr, 4-hr, 6-hr post-injection. Data are means ± sd. N = 3. **p < 0.01.

Abbreviations: PA, photoacoustic; MPDA-PEG-PTX, paclitaxel loaded polyethylene glycol-modified mesoporous polydopamine; PBS, phosphate buffer saline; NIR, near Infrared.