Fig. 5.

Cytokines significantly different between relapse and cured/failed patients. Serum sIL-2R alpha (pg/ml) (a) and CRP (ng/ml) (b) were determined in cured, failed and relapse patients at diagnosis, weeks 2, 4, and 26 of treatment and analyzed by a mixed model repeated measures ANOVA. Each data point represents the mean and the error bars denote the 95% confidence intervals. The letters a – f indicate statistical significance where values with the same letter are not significantly different from each other. The number of patients in each group at each time-point (n) is indicated above the x-axis. A p-value of <0.05 was regarded as significantly different.