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. Author manuscript; available in PMC: 2020 Sep 1.
Published in final edited form as: Pharmacol Res. 2019 Jul 25;147:104373. doi: 10.1016/j.phrs.2019.104373

Figure 6.

Figure 6.

Illustrative schemes of label-free technologies. A. Drug affinity responsive target stability (DARTS); B. Cellular thermal shift assay (CETSA); C. Thermal stability shift-based fluorescence difference in two-dimensional gel electrophoresis (TS-FITGE); D. Stability of proteins from rates of oxidation (SPROX); E. Size-exclusion chromatography for target identification (SEC-TID); F. Target identification by chromatography co-elution (TICC).