Structures of selected MNPs subjected to profiling methods, BioMAP
(arromycin), target-based profiling (isoarenarol, arenerol, brintonamide D,
amantamide, grassystatin A and lyngbyastatin 1), high-content screening
(bromophycolide A, microferrioxamine A–D, XR334, nocapyroneL and
quinocinnolinomycins A–D) and whole-organism screening (diketopiperazine
1 and compound 2). Pharmacophores for protease
inhibitors are highlighted.