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. 2019 Mar 6;68(11):1942–1952. doi: 10.1136/gutjnl-2018-316691

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© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Variation in disease susceptibility across 17 CC strains. (A) Tumour frequency and type across CC strains within 1 year. (B) Tumour-free survival across CC strains. (C) Representative H&E image of splenic lymphoma in CC037 mouse. (D) Representative H&E image of CC037 mouse liver (from C) showing numerous metastatic lymphoid lesions indicated by red arrows in enlargement. (E) Representative H&E image of CC040 mouse lung showing plant material obstructing a bronchus and surrounded by lymphocytic inflammation as indicated by the red arrow. (F) Representative H&E image of CC032 mouse kidney showing a polycystic phenotype. CC, Collaborative Cross.