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. Author manuscript; available in PMC: 2019 Nov 8.
Published in final edited form as: J Pain. 2017 Oct 12;19(1):99–110. doi: 10.1016/j.jpain.2017.08.011

Table 4.

Variations in associations between mental disorders and chronic back or neck pain by lifecourse timing of chronic back or neck pain onset.

Type of Mental Disorders Mental disorder*Person-year interaction1 Stratified Models2
Up to Age 24 Age 25-35 Age 36-47 Age 48+

OR (95% C.I.) χ21 [p] OR (95% C.I.) OR (95% C.I.) OR (95% C.I.) OR (95% C.I.)
Major Depressive Episode/ Dysthymia 0.98* (0.98-0.98) 87.7* [0.000] 1.8* (1.6-2.0) 1.4* (1.2-1.5) 1.3* (1.2-1.5) 1.3* (1.1-1.5)
Bipolar Disorder (Broad) 0.98* (0.97-0.99) 11.8* [0.001] 1.3* (1.0-1.7) 1.0 (0.7-1.4) 1.0 (0.6-1.4) 1.5 (0.9-2.4)
Panic Disorder 0.97* (0.96-0.98) 37.3* [0.000] 1.4* (1.1-1.8) 1.5* (1.2-1.9) 1.2 (0.9-1.5) 0.9 (0.6-1.3)
Generalized Anxiety Disorder 0.98* (0.97-0.99) 23.5* [0.000] 1.4* (1.1-1.7) 1.2* (1.0-1.5) 1.7* (1.4-2.1) 1.5* (1.2-1.9)
Social Phobia 0.98* (0.97-0.98) 68.4* [0.000] 1.3* (1.1-1.5) 1.3* (1.1-1.5) 1.0 (0.9-1.3) 0.9 (0.7-1.2)
Specific Phobia 0.99* (0.99-1.00) 16.4* [0.000] 1.4* (1.3-1.6) 1.5* (1.3-1.7) 1.5* (1.3-1.7) 1.5* (1.2-1.9)
Post-Traumatic Stress Disorder 0.98* (0.97-0.99) 21.6* [0.000] 1.2 (1.0-1.5) 1.4* (1.1-1.8) 1.3* (1.0-1.7) 1.2 (0.9-1.6)
Intermittent Explosive Disorder 0.99* (0.97-1.00) 7.8* [0.005] 1.5* (1.2-1.9) 1.5* (1.2-1.9) 1.3 (0.9-1.8) 1.5 (0.9-2.3)
Alcohol Abuse 0.97* (0.96-0.98) 59.0* [0.000] 1.4* (1.1-1.7) 1.3* (1.1-1.6) 1.3* (1.0-1.7) 1.0 (0.7-1.3)
Alcohol Dependence with Abuse 0.98* (0.96-0.99) 11.7* [0.001] 1.0 (0.8-1.4) 1.0 (0.7-1.4) 1.0 (0.7-1.4) 1.5 (1.0-2.5)
Drug Abuse 0.97* (0.95-0.99) 13.2* [0.000] 1.3 (1.0-1.8) 1.1 (0.8-1.4) 1.7* (1.1-2.4) 2.1* (1.2-3.7)
Drug Dependence with Abuse 0.96* (0.93-0.98) 11.1* [0.001] 0.8 (0.6-1.2) 0.9 (0.6-1.3) 0.6 (0.3-1.1) 0.2* (0.1-0.9)
*

OR significant at the 0.05 level, 2-sided test

1

A series of multivariate models were estimated. For example, the model for depression included the dummy variables for all mental disorders plus the cross-product term for depression and person-year (as a continuous variable), plus the controls specified for earlier models.

2

The multivariate model was estimated in the four person-year datasets corresponding to quartiles of the chronic back or neck pain onset distribution.