Table 2.

Patient disposition in the open-label extension study

	PF-04236921
Enrolled and treated*	191
Responder at entry	89
Non-responder at entry	99
Responder status missing at entry	3
End of treatment: completed	69
Baseline HBI data	65
Responders	36
Non-responders	29
End of treatment: discontinued	122
Baseline HBI data	121
Responders	51
Non-responders	70
End of study (includes follow-up period): completed	111
Analysed for safety	191
Analysed for efficacy	189†

*Patients in the prior induction study achieving CDAI-70 (proportion of patients who achieved a ≥70-point reduction in Crohn’s Disease Activity Index (CDAI) score) response were considered responders at entry and those patients not achieving CDAI-70 response were considered non-responders at entry.

†Patients who received at least one dose of PF-04236921 in this study but excludes two patients with a quality issue.

HBI, Harvey-Bradshaw Index.