Table 2. Clinical features of the NEC neonates.
| Fulminant NEC | Non-fulminant NEC | χχχ 2(Z) | P value | |
|---|---|---|---|---|
| (n = 112) | (n = 240) | |||
| Age of onset(days), mean(P25-P75) | 5.54(2.00–10.81) | 7.15(2.02–13.79) | (Z = 0.736) | 0.462 |
| Emesis | 51(45.54%) | 130(54.17%) | 2.277 | 0.131 |
| Abdominal distension | 107(95.54%) | 196(81.67%) | 12.258 | <0.001 |
| Gross bloody stool | 45(40.18%) | 101(42.08%) | 0.114 | 0.735 |
| Bowel sound | ||||
| Attenuation | 41(36.61%) | 122(50.83%) | 6.216 | 0.013 |
| Disappearance | 49(43.75%) | 61(25.42%) | 11.947 | 0.001 |
| Complete blood count | ||||
| Leukocytes <5*109/L | 42(38.53%) | 32(13.73%) | 26.933 | <0.001 |
| Leukocytes >20*109/L | 5(4.63%) | 34(14.66%) | 7.294 | 0.007 |
| Platelet ≤100*109/L | 23(21.10%) | 38(16.31%) | 1.164 | 0.281 |
| Hematocrit<22.0% | 5(4.59%) | 10(4.29%) | 0.000 | 1.000 |
| Neutrophils<1.5*109/L | 19(17.43%) | 7(3.00%) | 22.004 | <0.001 |
| Unknown | 3 | 7 | ||
| C-reactive protein≥10 mg/L | 69(64.49%) | 108(47.37%) | 8.563 | 0.003 |
| Unknown | 5 | 12 | ||
| Procalcitonin ≥2 ¶g/L | 48(84.21%) | 78(53.79%) | 16.131 | <0.001 |
| Unknown | 55 | 95 | ||
| pH≤7.2 | 23(29.87%) | 14(9.09%) | 16.477 | <0.001 |
| Unknown | 35 | 86 | ||
| Positive blood culture | 19(26.76%) | 32(21.33%) | 0.800 | 0.371 |
| Unknown | 41 | 90 | ||
| Abdominal radiography | ||||
| Portal venous air | 26(24.30%) | 51(21.43%) | 0.351 | 0.554 |
| Pneumatosis intestinalis | 42(39.25%) | 83(34.87%) | 0.612 | 0.434 |
| Pneumoperitoneum | 73(68.22%) | 97(40.76%) | 22.282 | <0.001 |
| Unknown | 5 | 2 | ||
| Abdominal ultrasonography | ||||
| Portal venous air | 20(37.74%) | 86(46.24%) | 1.208 | 0.272 |
| Pneumatosis intestinalis | 11(20.75%) | 30(16.13%) | 0.621 | 0.431 |
| Seroperitoneum | 45(84.91%) | 127(68.28%) | 5.652 | 0.017 |
| Unknown | 59 | 54 |