Skip to main content
. 2019 Nov 8;14(11):e0225008. doi: 10.1371/journal.pone.0225008

Table 6. Multiple linear regression analysis of the serum leptin and adiponectin concentration and the echocardiographic findings.

A) Dependent variable: leptin (log) Model 1 Model 2 Model 3 Model 4
Independent variable β-value (p) β-value (p) β-value (p) β-value (p)
LAD -0.310 (0.002)** -0.327 (0.001)** -0.306 (0.002)** -0.262 (0.002)**
EF (log) 0.123 (0.172) 0.120 (0.184) 0.064 (0.476) -0.021 (0.792)
LVMI (log) -0.215 (0.024)* -0.213 (0.026)* -0.200 (0.030)* -0.166 (0.036)*
E/e’ (log) -0.028 (0.753) -0.014 (0.878) -0.045 (0.612) 0.010 (0.893)
B) Dependent variable: LAVI (log) Model 1 Model 2 Model 3 Model 4
Independent variable β-value (p) β-value (p) β-value (p) β-value (p)
Leptin (log) -0.382 (0.000)*** -0.379 (0.000)*** -0.424 (0.000)*** -0.434 (0.000)***
Adiponectin (log) 0.373 (0.000)*** 0.426 (0.000)*** 0.397 (0.000)*** 0.398 (0.000)***
C) Dependent variable: E/e’ (log) Model 1 Model 2 Model 3 Model 4
Independent variable β-value (p) β-value (p) β-value (p) β-value (p)
Leptin (log) -0.014 (0.878) -0.016 (0.863) -0.049 (0.637) 0.013 (0.918)
Adiponectin (log) 0.306 (0.002)** 0.275 (0.008)** 0.255 (0.016)* 0.245 (0.022)*
D) Dependent variable: LVMI (log) Model 1 Model 2 Model 3 Model 4
Independent variable β-value (p) β-value (p) β-value (p) β-value (p)
Leptin (log) -0.331 (0.001)** -0.327 (0.001)** -0.306 (0.003)** -0.370 (0.003)**
Adiponectin (log) -0.005 (0.956) 0.020 (0.845) 0.032 (0.758) 0.041 (0.692)

* p < 0.05

** p < 0.01

*** p < 0.001 Model 1, unadjusted; Model 2, adjusted by age, Model 3, adjusted by age and sex, Model 4, adjusted by age, sex, and BMI