. 2019 Nov 8;14(11):e0224657. doi: 10.1371/journal.pone.0224657

Table 2. Comparison of in vitro 3D BMPS model data with in vivo LD₅₀ data on MUS, DXM, and EtOH toxicity.

Chemical	Toxicity (LC₅₀, mM) (95% CI)		In vivo (LD₅₀, mg/kg) (toxicity source)
MUS	1.159E-3	(3.592E-5 ~3.677E-2)	2.5	(Oral-mouse) [16]
DXM	3.863E-2	(1.860E-3 ~ 8.089E-1)	116	(Oral-rat) [17]
EtOH	5.240E1	(1.797E1 ~ 1.654E2)	7060	(Oral-rat) [18]

Table 2. Comparison of in vitro 3D BMPS model data with in vivo LD50 data on MUS, DXM, and EtOH toxicity.