Table 2. Univariate and multivariate Cox multiple regression analysis with respect to overall survival after surgery in 584 patients with gastric carcinoma.

	Univariate analysis		Multivariate analysis
	Hazard Ratio (95% CI)	p value	Hazard Ratio (95% CI)	p value
THBS4-high	3.43 (2.48–4.75)	<0.001	1.53 (1.05–2.25)	0.028
Age ≥65 year-old	1.61 (1.16–2.23)	0.004	1.74 (1.23–2.46)	0.002
Female (vs. Male)	1.29 (0.93–1.79)	0.123
αSMA-high	2.37 (1.70–3.31)	<0.001	1.27 (0.90–1.80)	0.180
Borrmann’s type 4	7.41 (5.22–10.5)	<0.001	1.62 (1.05–2.50)	0.042
Tumor diameter ≥50 mm	6.27 (4.37–9.00)	<0.001	1.49 (0.90–2.46)	0.088
Undifferentiated type	1.72 (1.24–2.37)	0.001	1.18 (0.81–1.70)	0.386
T3&4 (vs. T1&2)	6.72 (4.61–9.80)	<0.001	1.41 (0.82–2.40)	0.211
N1-3 (vs. N0)	8.29 (5.50–12.5)	<0.001	2.79 (1.62–4.80)	<0.001
Lymphatic invasion	5.22 (3.42–7.95)	<0.001	1.06 (0.61–1.83)	0.837
Vascular invasion	3.10 (2.22–4.32)	<0.001	1.06 (0.73–1.53)	0.772
Cytology positive	7.42 (5.23–10.5)	<0.001	1.91 (1.28–2.85)	0.001
Peritoneal metastasis	9.11 (5.97–13.9)	<0.001	2.60 (1.64–4.12)	<0.001
Hepatic metastasis	5.90 (3.18–11.0)	<0.001	3.64 (1.89–7.02)	<0.001