FIG 1.

(A) Maximal change of tumor size from baseline assessed by investigator per Response Evaluation Criteria in Solid Tumors (RECIST) version 1.1 (N = 33). The length of the bar represents maximal decrease or minimal increase in target lesion(s). (B) Change in individual tumor burden over time from baseline assessed by investigator per RECIST version 1.1 (N = 33). (C) Exposure and duration of response per RECIST version 1.1 (N = 33). (*) Patient with target lesion(s) reduction of more than 30% but with new lesion(s) or progression of nontarget lesion(s). (†) Unconfirmed partial response classified as stable disease. Mbp, million base pairs; PD-L1, programmed death ligand-1; TMB, tumor mutational burden.