Table 1.
Characteristic | Recurrence* | Control** | p-value |
---|---|---|---|
Patients, n (%) | 22 (50%) | 22 (50%) | |
Age at surgery (years)*** | 47 (29–63) | 50 (35–75) | 0.289 |
Tumor size (cm)*** | 3.3 (1.4–8.0) | 2.6 (1.5–5.5) | 0.044 |
Operation methods | 0.203 | ||
Partial mastectomy and sentinel lymph node biopsy | 1 (33%) | 2 (67%) | |
Partial mastectomy and axillary lymph node dissection | 1 (100%) | 0 | |
Total mastectomy and sentinel lymph node biopsy | 2 (100%) | 0 | |
Modified radical mastectomy | 18 (47%) | 20 (53%) | |
Tumor-infiltrating lymphocytes | |||
Low | |||
High | |||
Histology grade | >0.999 | ||
Nuclear grade II | 4 (44%) | 5 (56%) | |
Nuclear grade III | 18 (51%) | 17 (49%) | |
Extensive intraductal components | 10 (67%) | 5 (33%) | 0.203 |
Lymphatic tumor emboli | 13 (52%) | 12 (48%) | >0.999 |
Extranodal extension | 6 (67%) | 3 (33%) | 0.460 |
Tumor stage | 0.493 | ||
T1 | 1 (33%) | 2 (67%) | |
T2 | 18 (49%) | 19 (51%) | |
T3 | 3 (75%) | 1 (25%) | |
Nodal stage | 0.103 | ||
N0 | 9 (47%) | 10 (53%) | |
N1 | 6 (46%) | 7 (54%) | |
N2 | 3 (38%) | 5 (62%) | |
N3 | 4 (100%) | 0 | |
AJCC TNM stage | 0.168 | ||
Stage IA | 1 (33%) | 2 (9%) | |
Stage IIA | 7 (47%) | 8 (53%) | |
Stage IIB | 7 (50%) | 7 (50%) | |
Stage IIIA | 3 (37%) | 5 (63%) | |
Stage IIIC | 4 (100%) | 0 | |
Intrinsic subtypes | 0.716 | ||
Luminal A | 3 (37%) | 5 (63%) | |
Luminal B without Her-2/Neu overexpression | 3 (50%) | 3 (50%) | |
Luminal B with Her-2/Neu overexpression | 6 (67%) | 3 (33%) | |
Her-2/Neu overexpression | 3 (37%) | 5 (63%) | |
Triple-negative breast cancer | 7 (54%) | 6 (46%) |
AJCC TNM stage, American Joint Committee on Cancer tumor-node-metastases (TNM) staging system, 7th ed.
*Cancer recurrence within 24 months postoperatively. **No recurrence after 24 months postoperatively. ***Values are expressed as median (range).