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. 2019 Nov 8;9:16359. doi: 10.1038/s41598-019-52617-4

Table 1.

Characteristics of patients with breast cancer (n = 44). Comparison between recurrence and control patients was done.

Characteristic Recurrence* Control** p-value
Patients, n (%) 22 (50%) 22 (50%)
Age at surgery (years)*** 47 (29–63) 50 (35–75) 0.289
Tumor size (cm)*** 3.3 (1.4–8.0) 2.6 (1.5–5.5) 0.044
Operation methods 0.203
      Partial mastectomy and sentinel lymph node biopsy 1 (33%) 2 (67%)
      Partial mastectomy and axillary lymph node dissection 1 (100%) 0
      Total mastectomy and sentinel lymph node biopsy 2 (100%) 0
      Modified radical mastectomy 18 (47%) 20 (53%)
Tumor-infiltrating lymphocytes
     Low
     High
Histology grade >0.999
     Nuclear grade II 4 (44%) 5 (56%)
     Nuclear grade III 18 (51%) 17 (49%)
Extensive intraductal components 10 (67%) 5 (33%) 0.203
Lymphatic tumor emboli 13 (52%) 12 (48%) >0.999
Extranodal extension 6 (67%) 3 (33%) 0.460
Tumor stage 0.493
     T1 1 (33%) 2 (67%)
     T2 18 (49%) 19 (51%)
     T3 3 (75%) 1 (25%)
Nodal stage 0.103
     N0 9 (47%) 10 (53%)
     N1 6 (46%) 7 (54%)
     N2 3 (38%) 5 (62%)
     N3 4 (100%) 0
AJCC TNM stage 0.168
     Stage IA 1 (33%) 2 (9%)
     Stage IIA 7 (47%) 8 (53%)
     Stage IIB 7 (50%) 7 (50%)
     Stage IIIA 3 (37%) 5 (63%)
     Stage IIIC 4 (100%) 0
Intrinsic subtypes 0.716
     Luminal A 3 (37%) 5 (63%)
     Luminal B without Her-2/Neu overexpression 3 (50%) 3 (50%)
     Luminal B with Her-2/Neu overexpression 6 (67%) 3 (33%)
     Her-2/Neu overexpression 3 (37%) 5 (63%)
     Triple-negative breast cancer 7 (54%) 6 (46%)

AJCC TNM stage, American Joint Committee on Cancer tumor-node-metastases (TNM) staging system, 7th ed.

*Cancer recurrence within 24 months postoperatively. **No recurrence after 24 months postoperatively. ***Values are expressed as median (range).