Table 1.
List of genes significantly changed by progressive vascular endothelial damage (AI-30 group).
| Gene Symbol | mRNA Accession | AI-30/sham fold change | AI-30/sham p-value | Map Name |
|---|---|---|---|---|
| S100a9 | NM_053587 | 2.27 | 0.04 | IL-17 signaling pathway |
| Tf | NM_001013110 | 2.24 | 0.04 | HIF-1 signaling pathway |
| Csf3r | NM_001106685 | 2.19 | 0.01 | Cytokine-cytokine receptor interaction |
| Pathways in cancer | ||||
| Hmgcs2 | NM_173094 | 2.14 | 0.03 | Metabolic pathways |
| Pla2g2a | NM_031598 | 2.09 | 0.00 | Ether lipid metabolism |
| Metabolic pathways | ||||
| Pancreatic secretion | ||||
| Cxcl2 | NM_053647 | 2.02 | 0.05 | Cytokine-cytokine receptor interaction |
| IL-17 signaling pathway | ||||
| Kaposi’s sarcoma-associated herpesvirus infection | ||||
| Ifit1bl | XM_001079971 | 1.98 | 0.04 | Hepatitis C |
| Herpes simplex infection | ||||
| Cfh | NM_130409 | 1.98 | 0.05 | Staphylococcus aureus infection |
| Car2 | NM_019291 | 1.95 | 0.04 | Proximal tubule bicarbonate reclamation |
| Pancreatic secretion | ||||
| Slc4a4 | NM_053424 | 1.86 | 0.01 | Proximal tubule bicarbonate reclamation |
| Pancreatic secretion | ||||
| Nfkbia | NM_001105720 | 1.83 | 0.04 | Osteoclast differentiation |
| IL-17 signaling pathway | ||||
| Hepatitis C | ||||
| Measles | ||||
| Influenza A | ||||
| Kaposi’s sarcoma-associated herpesvirus infection | ||||
| Herpes simplex infection | ||||
| Pathways in cancer | ||||
| C2 | NM_172222 | 1.80 | 0.01 | Staphylococcus aureus infection |
| Ces2g | NM_001106175 | 1.79 | 0.04 | Drug metabolism - other enzymes |
| Fcgr2b | NM_175756 | 1.78 | 0.01 | Osteoclast differentiation |
| Staphylococcus aureus infection | ||||
| Measles | ||||
| Vegfa | NM_001110333 | 1.71 | 0.04 | Cytokine-cytokine receptor interaction |
| HIF-1 signaling pathway | ||||
| Kaposi’s sarcoma-associated herpesvirus infection | ||||
| Pathways in cancer | ||||
| Ptafr | NM_053321 | 1.68 | 0.04 | Staphylococcus aureus infection |
| Il33 | NM_001014166 | 1.59 | 0.04 | Influenza A |
| B3gnt5 | NM_053932 | 1.59 | 0.01 | Metabolic pathways |
| Ifngr1 | NM_053783 | 1.51 | 0.01 | Cytokine-cytokine receptor interaction |
| HIF-1 signaling pathway | ||||
| Osteoclast differentiation | ||||
| Measles | ||||
| Influenza A | ||||
| Kaposi’s sarcoma-associated herpesvirus infection | ||||
| Herpes simplex infection | ||||
| Pathways in cancer | ||||
| Pla2g7 | NM_001009353 | 1.51 | 0.03 | Ether lipid metabolism |
| Metabolic pathways | ||||
| Pancreatic secretion | ||||
| Agps | ENSRNOT00000002111 | −1.50 | 0.00 | Ether lipid metabolism |
| Cldn23 | NM_001033062 | −1.65 | 0.01 | Hepatitis C |
| Sc5d | NM_053642 | −1.82 | 0.05 | Metabolic pathways |
| Cmpk1 | NM_001025655 | −2.19 | 0.05 | Drug metabolism - other enzymes |
| Metabolic pathways | ||||
| Cda | NM_001108688 | −2.91 | 0.02 | Drug metabolism - other enzymes |
| Metabolic pathways |