Table 3.
Co-overexpression of EZH2 and cyclin E genes in breast cancers
| Basal-like | HER2 | Luminal A | Luminal B | Normal-like | |
|---|---|---|---|---|---|
| EZH2/CCNE1 OE | |||||
| Sample size, n | 91 | 116 | 130 | 172 | 6 |
| Yes | 84 | 82 | 43 | 33 | 1 |
| % Co-OE | 92.3 | 70.7 | 33.1 | 19.2 | 16.7 |
| EZH2/CCNE2 OE | |||||
| Sample size, n | 91 | 116 | 130 | 172 | 6 |
| Yes | 78 | 93 | 75 | 54 | 0 |
| % Co-OE | 85.7 | 80.2 | 57.7 | 31.4 | 0 |
TCGA RNAseq Data set were downloaded from Broad Institute Firehose website (https://gdac.broadinstitute.org; BRCA cohort). Co-overexpression of EZH2 and CCNE1 or CCNE2 was analyzed as described in Tables 1 and 2