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Effect of FBS and HSA on IC50 values for ruxolitinib-dependent K562, HEL and SET-2 cell viability.
| IC50 (μM) | ||||||
|---|---|---|---|---|---|---|
| Cell type | 10% FBS | 80 μM HSA | 8 μM HSA | 0.8 μM HSA | 0.08 μM HSA | no HSA |
| K562 | >10 | >10 | >10 | >10 | >10 | >10 |
| HEL | 4.7 ± 1.0 | 4.1 ± 0.8 | 3.1 ± 0.6 | 2.2 ± 0.5 | 1.7 ± 0.4 | 1.0 ± 0.3 |
| SET-2 | 0.15 ± 0.04 | 0.10 ± 0.03 | 0.033 ± 0.005 | 0.032 ± 0.004 | 0.035 ± 0.008 | 0.033 ± 0.008 |
