. 2019 Nov 8;9:16340. doi: 10.1038/s41598-019-52659-8

Table 2.

Parameters of vascular network morphology of the whole retina in pathological states.

Diagnosis	DR	G	H	p-value
Box counting dimension (Db) mean ± SD	1.57 ± 0.03	1.58 ± 0.02	1.57 ± 0.02	0.23
Lacunarity (Λ) mean ± SD	0.37 ± 0.06^a	0.34 ± 0.03^ab	0.33 ± 0.02^b	0.03*
Skeletonized vessel density mean[%] ± SD	26.11 ± 2.90	27.39 ± 2.26	26.9 ± 2.06	0.359

Diagnosis

p-value

Box counting dimension (Db)

mean ± SD

1.57 ± 0.03

1.58 ± 0.02

1.57 ± 0.02

0.23

Lacunarity (Λ)

mean ± SD

0.37 ± 0.06^a

0.34 ± 0.03^ab

0.33 ± 0.02^b

0.03*

Skeletonized vessel density

mean[%] ± SD

26.11 ± 2.90

27.39 ± 2.26

26.9 ± 2.06

0.359

All analyses were performed on skeletonized images. *P- values < 0.05 are considered significant. Groups labelled with different letters are statistically different.