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. 2019 Nov 8;9:16323. doi: 10.1038/s41598-019-51781-x

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Both diet and L. brevis had a significant impact on gut microbiota composition. Relative abundance of microbial taxa at (A) phylum and (B) genus level. Phyla and genera representing <0.1% abundance in any sample were considered as Other. The PCA plot based on OTU relative abundances of the bacterial community and the metabolic parameters measured in mice (C). The first two principal coordinates (PC1 and PC2) are plotted for each sample (D), with the variables related to the variance between groups. PCA: Principal Component Analysis, OTU; Operational Taxonomy Unit.