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. Author manuscript; available in PMC: 2019 Nov 9.
Published in final edited form as: Leukemia. 2019 May 9;33(11):2599–2609. doi: 10.1038/s41375-019-0477-x

Table 4.

Multivariate analysis for TRM, relapse, DFS and OS within the AlloHCT group

TRM Relapse DFS OS
Variables HR (95% CI) P-value HR (95% CI) P-value HR (95% CI) P-value HR (99% CI) P-value
Conditioning Intensity
 MAC 1 1 1 1
 NMA/RIC 0.99 (0.65–1.51) 0.95 1.39 (0.93–2.08) 0.11 1.19 (0.89–1.59) 0.24 1.14 (0.85–1.54) 0.39
Donor Type 0.0004 0.07 0.0003 <0.0001
 HLA-identical sibling 1 1 1 1
 HLA Partially MURD/MMURD 1.47 (0.75–2.88) 0.26 0.70 (0.38–1.26) 0.23 0.94 (0.61–1.46) 0.79 1.05 (0.66–1.65) 0.85
 HLA-Well-matched URD 1.23 (0.74–2.04) 0.42 0.73 (0.5–1.06) 0.1 0.88 (0.66–1.20) 0.44 0.97 (0.71–1.33) 0.85
 UCB 2.69 (1.59–4.55) 0.0002 1.18 (0.77–1.8) 0.45 1.65 (1.19–2.28) 0.003 1.87 (1.34–2.60) 0.0002

Abbreviations: TRM: treatment-related mortality, DFS: disease-free survival, OS: overall survival, HR: hazard ratio, MAC: myeloablative conditioning, NMA: nonmyeloablative, RIC: reduced-intensity conditioning, MURD: matched unrelated donor, MMURD: mismatched unrelated donor, URD: unrelated donor, UCB: umbilical cord blood.