Table 4.
TRM | Relapse | DFS | OS | |||||
---|---|---|---|---|---|---|---|---|
Variables | HR (95% CI) | P-value | HR (95% CI) | P-value | HR (95% CI) | P-value | HR (99% CI) | P-value |
Conditioning Intensity | ||||||||
MAC | 1 | 1 | 1 | 1 | ||||
NMA/RIC | 0.99 (0.65–1.51) | 0.95 | 1.39 (0.93–2.08) | 0.11 | 1.19 (0.89–1.59) | 0.24 | 1.14 (0.85–1.54) | 0.39 |
Donor Type | 0.0004 | 0.07 | 0.0003 | <0.0001 | ||||
HLA-identical sibling | 1 | 1 | 1 | 1 | ||||
HLA Partially MURD/MMURD | 1.47 (0.75–2.88) | 0.26 | 0.70 (0.38–1.26) | 0.23 | 0.94 (0.61–1.46) | 0.79 | 1.05 (0.66–1.65) | 0.85 |
HLA-Well-matched URD | 1.23 (0.74–2.04) | 0.42 | 0.73 (0.5–1.06) | 0.1 | 0.88 (0.66–1.20) | 0.44 | 0.97 (0.71–1.33) | 0.85 |
UCB | 2.69 (1.59–4.55) | 0.0002 | 1.18 (0.77–1.8) | 0.45 | 1.65 (1.19–2.28) | 0.003 | 1.87 (1.34–2.60) | 0.0002 |
Abbreviations: TRM: treatment-related mortality, DFS: disease-free survival, OS: overall survival, HR: hazard ratio, MAC: myeloablative conditioning, NMA: nonmyeloablative, RIC: reduced-intensity conditioning, MURD: matched unrelated donor, MMURD: mismatched unrelated donor, URD: unrelated donor, UCB: umbilical cord blood.