Table 4.
Regression coefficients for associations of maternal 2nd trimester erythrocyte lead levels with SDQ scores in mid-childhood (n=1006)
| Model 1a β (95% CI) |
Model 2b β (95% CI) |
|
|---|---|---|
| Parent-rated SDQ Scales | ||
| Total Difficulties | 0.40 (0.01, 0.79) | 0.36 (−0.04, 0.77) |
| Peer | 0.07 (−0.05, 0.20) | 0.06 (−0.06, 0.19) |
| Hyperactivity | 0.10 (−0.08, 0.28) | 0.06 (−0.12, 0.25) |
| Emotional | 0.18 (0.04, 0.32) | 0.18 (0.03, 0.33) |
| Conduct | 0.05 (−0.07, 0.17) | 0.06 (−0.06, 0.18) |
| Prosocial | −0.09 (−0.22, 0.04) | −0.08 (−0.21, 0.05) |
| Teacher-rated SDQ Scales | ||
| Total Difficulties | 0.30 (−0.23, 0.83) | 0.38 (−0.15, 0.91) |
| Peer | 0.09 (−0.06, 0.23) | 0.11 (−0.04, 0.25) |
| Hyperactivity | 0.10 (−0.16, 0.36) | 0.12 (−0.14, 0.39) |
| Emotional | 0.01 (−0.16, 0.18) | 0.04 (−0.13, 0.21) |
| Conduct | 0.10 (−0.05, 0.26) | 0.11 (−0.05, 0.26) |
| Prosocial | −0.11 (−0.29, 0.06) | −0.12 (−0.30, 0.06) |
Note: Coefficients represent change in score for an IQR increase in maternal erythrocyte lead (0.6 μg/dL); Total Difficulties is calculated by summing the scales of emotional problems, conduct problems, hyperactivity, and peer relationship problems; Higher scores indicate worse performance on all scales with the exception of the prosocial behavior scale. The prosocial behavior scale is scored in the opposite direction.
Model 1: Adjusted for child age and sex.
Model 2: Model 1 additionally adjusted for maternal 2nd trimester mercury and manganese levels, nulliparity, smoking during pregnancy, IQ, and education; paternal education; HOME composite score and household income; and child race/ethnicity.