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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Cell Microbiol. 2019 Jul 8;21(11):e13070. doi: 10.1111/cmi.13070

Figure 1. Progression of toxoplasmosis.

Figure 1.

(A) T. gondii infections are acquired when hosts ingest parasite cysts. Upon reaching the ileum, parasites released from the cysts traverse invade through intestinal epithelium and gain access to the lamina propria. (B) T. gondii then spreads systemically. Parasites may invade the CNS when extracellular T. gondii directly invade BBB endothelial cells or with the assistance of migratory infected leukocytes using Trojan horse or hitchhiker mechanisms.