a Effects of knockdown of FGFR1 and FGFR3 on neurobehavioral scores at 24 h after modeling (n = 6 per group). * P < 0.05. b Representative western blot images and densitometric quantification of expression of PI3k, phosphorylated Akt (p-Akt), Bcl-2, and Bax. Expression levels of each protein are expressed as mean ± standard deviation (n = 6 per group). * P < 0.05, ** P < 0.01. rFGF-2, recombinant fibroblast growth factor-2; siRNA, small interfering ribonucleic acid; Scr siRNA, scrambled siRNA.