Table 3.
Correlations Between Expression Of MST4 In GC Tissues And Clinicopathologic Parameters Of Patients With GC In The Validation Cohort
| Clinicopathologic Parameters | n | MST4 Expression | P | |
|---|---|---|---|---|
| Low (54) | High (66) | |||
| Gender | ||||
| Male | 84 | 39 | 45 | |
| Female | 36 | 15 | 21 | 0.692 |
| Age (y) | ||||
| ≤60 | 64 | 30 | 34 | |
| >60 | 56 | 24 | 32 | 0.715 |
| Tumor size (cm) | ||||
| ≤5 | 46 | 18 | 28 | |
| >5 | 74 | 36 | 38 | 0.349 |
| Grade of differentiation | ||||
| Well and moderate | 51 | 27 | 24 | |
| Poor and not | 69 | 27 | 42 | 0.133 |
| Lauren’s classification | ||||
| Intestinal | 88 | 44 | 44 | |
| Diffuse | 32 | 10 | 22 | 0.096 |
| Lymph node metastasis | ||||
| Negative | 45 | 31 | 14 | |
| Positive | 75 | 23 | 52 | <0.001 |
| Lymphovascular invasion | ||||
| Negative | 89 | 48 | 41 | |
| Positive | 31 | 6 | 25 | 0.001 |
| TNM stage | ||||
| I & II | 62 | 29 | 33 | |
| III | 58 | 25 | 33 | 0.688 |
Abbreviations: GC, gastric cancer; TNM, tumor node metastasis; MST4, mammalian sterile-20-like kinase 4.