Fig. 4.

Tight junction and tight junction-associated proteins are direct targets of miR-132 and miR-212. Luciferase activity levels were measured upon co-transfection of a luciferase construct containing 3′-UTR of claudin-1 (Cldn1) (a), junctional adhesion molecule 3 (Jam3) (b), occludin (Ocln) (c), or tight junction-associated protein 1 (Tjap1) (d), respectively, with pre-miR-132 or pre-mir-212. Data are presented as an average of three independent experiments with standard deviations, *p < 0.05