Table 5:

Associations of covariates with all-cause and cardiovascular mortality in full model (Model C)

	All-Cause		Cardiovascular
	HR (95% CI)	P value	HR (95% CI)	P value
Age	1.08 (1.06, 1.09)	<0.001	1.05 (1.03, 1.08)	<0.001
Male Sex	1.56 (1.10, 2.22)	0.013	1.23 (0.67, 2.24)	0.507
White	1.38 (1.18, 1.60)	<0.001	1.66 (1.16, 2.36)	0.005
Tobacco use at enrollment
Never	Ref.	Ref.	Ref.	Ref.
Former	1.25 (1.08, 1.45)	0.003	1.08 (0.55, 2.12)	0.833
Current	2.12 (1.75, 2.57)	<0.001	1.42 (0.77, 2.62)	0.258
BMI, kg/m2
<20	1.86 (1.48, 2.34)	<0.001	1.59 (0.91, 2.77)	0.103
20–25	Ref.	Ref.	Ref.	Ref.
>25 to ≤ 30	0.84 (0.72, 0.99)	0.037	0.73 (0.50, 1.07)	0.109
>30 to ≤35	0.67 (0.60, 0.74)	<0.001	0.85 (0.68, 1.06)	0.156
>35	0.85 (0.62, 1.16)	0.307	0.92 (0.46, 1.85)	0.815
RDCI score	1.24 (1.17, 1.32)	<0.001	1.19 (1.10, 1.28)	<0.001
Chronic kidney disease	1.71 (1.41, 2.08)	<0.001	2.17 (1.78, 2.65)	<0.001
DAS28
Remission	Ref.	Ref.	Ref.	Ref.
Low	1.33 (1.09, 1.64)	0.006	1.31 (0.94, 1.82)	0.111
Moderate	1.61 (1.39, 1.86)	<0.001	1.65 (1.21, 2.26)	0.002
High	1.89 (1.46, 2.43)	<0.001	1.71 (1.15, 2.56)	0.008
Prednisone use	1.21 (1.04, 1.41)	0.016	1.25 (1.04, 1.50)	0.019
Gout	1.03 (0.72, 1.48)	0.876	1.67 (0.85, 3.26)	0.136

^*BMI = body mass index; RDCI = Rheumatic Disease Comorbidity Index; DAS28 = 28-joint Disease Activity Score; significant associations shown in bold.