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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: J Allergy Clin Immunol. 2019 Jul 11;144(5):1228–1241.e9. doi: 10.1016/j.jaci.2019.06.037

Figure 2.

Figure 2.

CCL26 mRNA and protein are higher in fresh NECs from CRSwNP compared to HCs and correlated with 15LO1 expression. Total RNA and protein from freshly brushed NECs were harvested for RT-PCR and ELISA analysis. (A) CCL26 mRNA is higher in NECs of NP from CRSwNP subjects compared to HCs. (B) CCL26 mRNA expression correlated with 15LO1 mRNA ex vivo. (C) CCL26 protein (by ELISA) is higher in NECs of MT and NP cell lysates from CRSwNP subjects, especially NP, compared to HCs. (D) CCL26 protein (by ELISA) expression correlates with 15LO1 protein expression (by WB) in NP cell lysates. Abbreviations: NECs=nasal epithelial cells, HC=healthy controls, NP=nasal polyps, MT=middle turbinate, and CRSwNP=chronic rhinosinusitis with nasal polyps.