Table 8.
Items | Salmonella trial | ETEC F4 trial | ||||||
---|---|---|---|---|---|---|---|---|
CTR | DIC | RSE | P | CTR | DIC | RSE | P | |
Villus height, μm | ||||||||
4 PI | 185 | 183 | 65.5 | 0.962 | 278 | 229 | 89.4 | 0.289 |
8 PI | 282 | 276 | 58.1 | 0.852 | 323 | 321 | 63.7 | 0.955 |
Crypt depth, μm | ||||||||
4 PI | 315 | 323 | 69.6 | 0.815 | 196 | 182 | 30.9 | 0.38 |
8 PI | 300 | 290 | 37.1 | 0.596 | 189 | 184 | 19.7 | 0.600 |
Villus:Crypt | ||||||||
4 PI | 0.60 | 0.63 | 0.257 | 0.841 | 1.47 | 1.29 | 0.469 | 0.454 |
8 PI | 0.99 | 0.99 | 0.209 | 0.944 | 1.78 | 1.79 | 0.364 | 0.935 |
MIT, cells/100 μm | ||||||||
4 PI | 0.251 | 0.325 | 0.160 | 0.39 | 0.078 | 0.068 | 0.103 | 0.845 |
8 PI | 0.075 | 0.099 | 0.082 | 0.569 | 0.104 | 0.091 | 0.141 | 0.862 |
GC, cells/100 μm | ||||||||
4 PI | 2.20 | 1.93 | 0.851 | 0.556 | 1.75 | 1.43 | 0.542 | 0.262 |
8 PI | 1.49 | 1.28 | 0.548 | 0.457 | 1.31 | 1.33 | 0.519 | 0.954 |
IEL, cells/100 μm | ||||||||
4 PI | 2.92 | 2.76 | 1.509 | 0.841 | 2.07 | 2.04 | 0.482 | 0.917 |
8 PI | 3.92 | 3.06 | 0.882 | 0.072 | 2.39 | 2.88 | 0.523 | 0.080 |
GC Goblet cells in the villus, IEL Intraepithelial lymphocytes in the villus, MIT Mitoses in the crypt, PI Post-inoculation day, RSE Residual standard error