Table 1.

Effects of matrix fixation and NHE1 expression on cell migration and morphology

Matrix	Native		Fixed
NHE1 expression	Mock control (n = 30; N = 5)	Overexpressed (n = 40; N = 3)	Mock control (n = 40; N = 3)	Overexpressed (n = 41; N = 3)
Speed [µm min−1]	0.44 ± 0.03	0.034 ± 0.02	0.48 ± 0.04	0.13 ± 0.01
Net distance [µm]	61.92 ± 9.42	45.17 ± 5.6	57.92 ± 9.07	11.93 ± 2.33
Total distance [µm]	130.92 ± 8.61	103.12 ± 5.78	143.37 ± 10.67	37.84 ± 2.83
Directionality	0.45 ± 0.05	0.44 ± 0.04	0.38 ± 0.04	0.28 ± 0.04
Structural index	0.43 ± 0.03	0.5 ± 0.02	0.3 ± 0.01	0.42 ± 0.02
Area [µm2]	888 ± 112	1115 ± 84	1251 ± 78	1298 ± 94

Data are shown as mean ± SEM For p values and further information, please see text