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Cartoon representation of intermediates specific to 4 proposed mechanisms for icosahedral ssRNA virus growth. (A) Nucleation−elongation model (7–9). (B) Micellar condensation (“en masse”) (10). (C) RNA antenna model (11). (D) PS-mediated sequential assembly model (14). Arrows indicate impending binding events, vivid hues indicate interfaces activated for binding, and subdued hues represent subunits stabilized in postassembly conformations. CP, coat protein.
